{"created":"2023-07-25T09:59:23.096092+00:00","id":2260,"links":{},"metadata":{"_buckets":{"deposit":"f75cf2ec-7800-463c-8fcb-7fb426d88d5c"},"_deposit":{"created_by":4,"id":"2260","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"2260"},"status":"published"},"_oai":{"id":"oai:nfu.repo.nii.ac.jp:00002260","sets":["5:86"]},"author_link":["5692","5693","4739","4737","5696","5694","5695","5691"],"item_1_alternative_title_5":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_alternative_title":"デンキ　シゲキ　ニ　ヨル　バイヨウ　コッカクキン　サイボウ　ノ　ヒダイ　コウカ"}]},"item_1_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-03-30","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"日本福祉大学健康科学論集"},{"bibliographic_title":"Journal of health sciences, Nihon Fukushi University","bibliographic_titleLang":"en"}]}]},"item_1_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"岩田, 全広"},{"creatorName":"イワタ, マサヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4737","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西浜, かすり"},{"creatorName":"ニシハマ, カスリ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"5691","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"土田, 和可子"},{"creatorName":"ツチダ, ワカコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"5692","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 重行"},{"creatorName":"スズキ, シゲユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"5693","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Iwata, Masahiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4739","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nishihama, Kasuri","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"5694","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuchida, Wakako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"5695","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Shigeyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"5696","nameIdentifierScheme":"WEKO"}]}]},"item_1_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Electrical pulse stimulation （EPS） has a hypertrophic effect on mammalian skeletal muscle, and it is usually used to prevent muscle atrophy and improve muscle strength during rehabilitation therapy. However, there is no clear explanation for the mechanisms of how EPS induces muscle hypertrophy. Thus, to clarify the mechanisms, we performed cell culture of skeletal myotubes （C2C12 myotubes）. This culture was stimulated for 3 days, and the morphology of the hypertrophied myotube was analyzed. EPS conditions were as follows: rectangular wave; pulse frequency, 1.0 Hz; pulse duration, 2.5 msec; voltage, 50 V; and stimulation time, 5 min/h. Accordingly, observation under a microscope revealed that fully differentiated C2C12 myotubes contracted synchronously by EPS. In addition, diameters of the myotubes, taking as indicators of muscle hypertrophy, were analyzed. Diameters of the stimulated cells were significantly increased, compared to the diameters of those that were not stimulated. These results suggest that EPS induces to the hypertrophy of the C2C12 myotubes.","subitem_description_type":"Other"}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA12406697","subitem_source_identifier_type":"NCID"}]},"item_1_text_2":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_text_value":"原著論文"}]},"item_1_text_3":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Original"}]},"item_1_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"日本福祉大学健康科学部"},{"subitem_text_value":"医療法人三仁会あさひ病院リハビリテーション科"},{"subitem_text_value":"日本福祉大学健康科学部実習教育センター"},{"subitem_text_value":"名古屋大学大学院医学系研究科"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-03-30"}],"displaytype":"detail","filename":"kenkou16-02-iwata.pdf","filesize":[{"value":"366.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"kenkou16-02-iwata","url":"https://nfu.repo.nii.ac.jp/record/2260/files/kenkou16-02-iwata.pdf"},"version_id":"118773d3-9954-472e-ac2a-578afdff1821"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"電気刺激，筋肥大，培養骨格筋細胞，C2C12筋管細胞","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"電気刺激による培養骨格筋細胞の肥大効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"電気刺激による培養骨格筋細胞の肥大効果"},{"subitem_title":"The Hypertrophic Effect of Electrical Pulse Stimulation on Cultured Skeletal Muscle Cells","subitem_title_language":"en"}]},"item_type_id":"1","owner":"4","path":["86"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-03-30"},"publish_date":"2013-03-30","publish_status":"0","recid":"2260","relation_version_is_last":true,"title":["電気刺激による培養骨格筋細胞の肥大効果"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-07-25T10:33:37.826647+00:00"}